Tackles
Brian Urlacher (CHI) - 89
Jon Beason (CAR) - 81
Patrick Willis (CLE) - 81
Ernie Sims (DET) - 79
D'Qwell Jackson (ATL) - 79
Sacks
Cullen Jenkins (GB) - 10
C.J. Mosley (NYJ) - 10
Reggie Hayward (JAX) - 10
Charles Grant (NO) - 9
Derrick Burgess (OAK) - 9
(1 other tied with 9)
Interceptions
Ken Lucas (TEN) - 5
Terrence McGee (NYG) - 5
Walt Harris (SF) - 5
Sam Madison (BUF) - 5
Dunta Robinson (HOU) - 4
(4 others tied with 4)
Passer Rating
Derek Anderson (NYG) - 106.5
Donovan McNabb (NYJ) - 104.3
Tom Brady (NE) - 104.1
Peyton Manning (IND) - 101.7
Tony Romo (NYG) - 98.0
Eli Manning (SD) - 97.0
Ben Roethlisberger (PIT) - 95.9
Carson Palmer (CIN) - 95.9
Matt Moore (CAR) - 92.7
Rushing
Marshawn Lynch (PHI) - 1,255
Steven Jackson (NYG) - 1,217
Brian Westbrook (TEN) - 1,143
Fred Taylor (DEN) - 1,132
Ryan Grant (GB) - 1,045
Willie Parker (STL) - 1,021
Brandon Jacobs (BAL) - 1,008
Marion Barber (DAL) - 997
Reggie Bush (NO) - 924
Clinton Portis (WAS) - 905
Receiving
Steve Smith (NYG) - 947
Bernard Berrian (MIN) - 889
Larry Fitzgerald (ARZ) - 842
Terrell Owens (DAL) - 772
Chad Ocho Cinco (CIN) - 768
Reggie Williams (ARZ) - 758
Anquan Boldin (JAX) - 756
Randy Moss (NE) - 693
Joey Galloway (TB) - 652
Andre Johnson (HOU) - 649
Blocking
Brandon Moore (NYJ) - 76
Jahri Evans (NO) - 70
David Baas (SF) - 70
Kendall Simmons (PIT) - 68
Ben Grubbs (BAL) - 65
Claude Terrell (TEN) - 64
Justin Hartwig (PIT) - 64
Cooper Carlisle (OAK) - 63
Chris Snee (DET) - 63
Flozell Adams (BAL) - 62
(3 others tied with 62)